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细胞膜荧光探针BTA-2 CAS 10205-62-6

英文名称:BTA-2 [2-(4'-(dimethylamino)phenyl)-6-methyl-benzothiazole]
产品参数
Ex (nm)355Em (nm)426
分子量268.38溶剂DMSO
存储条件在零下15度以下保存, 避免光照
产品概述

产品基本信息

产品名称:细胞膜荧光探针BTA-2

CAS:10205-62-6

储存条件:-15℃避光防潮

保质期:24个月

 

产品物理化学光谱特性

分子量:268.38

溶剂:DMSO

激发波长(nm):355

发射波长(nm):426

 

产品介绍

BSB是一种细胞可渗透的荧光探针,在体外(Ki = 400 nM)和体内均可特异性结合并标记细胞内β-淀粉样蛋白聚集体。 它可作为阿尔茨海默氏病动物模型的诊断工具。百萤生物是AAT Bioquest的中国代理商,为您提供优质的细胞膜荧光探针BSB。 

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参考文献

Efficient radiosynthesis of carbon-11 labelled uncharged Thioflavin T derivatives using [11C]methyl triflate for beta-amyloid imaging in Alzheimer's Disease with PET
Authors: Solbach C, Uebele M, Reischl G, Machulla HJ.
Journal: Appl Radiat Isot (2005): 591

Mechanism of A beta(1-40) fibril-induced fluorescence of (trans,trans)-1-bromo-2,5-bis(4-hydroxystyryl)benzene (K114)
Authors: LeVine H, 3rd.
Journal: Biochemistry (2005): 15937

Multiple ligand binding sites on A beta(1-40) fibrils
Authors: LeVine H, 3rd.
Journal: Amyloid (2005): 5

Amyloid imaging probes are useful for detection of prion plaques and treatment of transmissible spongiform encephalopathies
Authors: Ishikawa K, Doh-ura K, Kudo Y, Nishida N, Murakami-Kubo I, Ando Y, Sawada T, Iwaki T.
Journal: J Gen Virol (2004): 1785

Development of a PET/SPECT agent for amyloid imaging in Alzheimer's disease
Authors: Wang Y, Klunk WE, Debnath ML, Huang GF, Holt DP, Shao L, Mathis CA.
Journal: J Mol Neurosci (2004): 55

In-vivo imaging of Alzheimer disease beta-amyloid with [11C]SB-13 PET
Authors: Verhoeff NP, Wilson AA, Takeshita S, Trop L, Hussey D, Singh K, Kung HF, Kung MP, Houle S.
Journal: Am J Geriatr Psychiatry (2004): 584

The binding of 2-(4'-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component
Authors: Klunk WE, Wang Y, Huang GF, Debnath ML, Holt DP, Shao L, Hamilton RL, Ikonomovic MD, DeKosky ST, Mathis CA.
Journal: J Neurosci (2003): 2086