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活性氧 ROS荧光探针 CDCF

英文名称:CDCF [5-(and-6)-Carboxy-2',7'-dichlorofluorescein] *Mixed isomers*
产品参数
Ex (nm)505Em (nm)526
分子量445.21溶剂DMSO
存储条件在零下15度以下保存, 避免光照
产品概述

产品基本信息

产品名称:活性氧ROS荧光探针 CDCF

CAS:111843-78-8

储存条件:-15℃避光防潮

保质期:12个月

 

产品物理化学光谱特性

分子量:445.21

外观:橘色固体

溶剂:DMSO

激发波长(nm):504

发射波长(nm):525

 

产品介绍

活性氧ROS荧光探针 CDCF是美国AAT Bioquest生产的用于检测活性氧的荧光探针。CDCF是5(6) - 羧基-2',7'-二氯二氢荧光素二乙酸酯和5(6) - 羧基-2',7'的荧光产物。细胞渗透性5(6) - 羧基-2',7'-二氯二氢荧光素二乙酸酯(H2DCFDA)(也称为二氯荧光素二乙酸酯)是化学还原形式的荧光素,用作细胞中活性氧(ROS)的指示剂, 例如,检测中性粒细胞和巨噬细胞中活性氧中间体的产生。 在通过细胞内酯酶和氧化裂解乙酸酯基团后,非荧光H2DCFDA转化为高荧光CDCF。 5(6) - 羧基-2',7'-二氯荧光素二乙酸酯染色用于研究多药耐药性蛋白[MRP和P-糖蛋白(Pgp)]。百萤生物是AAT Bioquest的中国代理商,为您提供优质的活性氧ROS荧光探针 CDCF。 

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活性氧(ROS)篇:包含总ROS和多种活性氧离子检测试剂大全

 

参考文献

Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice
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CTLA-4IG suppresses reactive oxygen species by preventing synovial adherent cell-induced inactivation of Rap1, a Ras family GTPASE mediator of oxidative stress in rheumatoid arthritis T cells
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Effect of culture conditions on the expression and function of Bsep, Mrp2, and Mdr1a/b in sandwich-cultured rat hepatocytes
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Journal: Biochem Pharmacol (2006): 1520

Kinetic validation of the use of carboxydichlorofluorescein as a drug surrogate for MRP5-mediated transport
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Journal: Eur J Pharm Sci (2006): 524

Listeria innocua and Lactobacillus delbrueckii subsp. bulgaricus employ different strategies to cope with acid stress
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Journal: Int J Food Microbiol (2006): 1

Non-destructive micromethod for MRP1 functional assay in human lung tumor cells
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Journal: Arch Toxicol (2006): 125

Role of oxidative stress in the apoptosis of hepatocellular carcinoma induced by combination of arsenic trioxide and ascorbic acid
Authors: Li JJ, Tang Q, Li Y, Hu BR, Ming ZY, Fu Q, Qian JQ, Xiang JZ.
Journal: Acta Pharmacol Sin (2006): 1078

A plasma membrane H+-ATPase is required for the formation of proanthocyanidins in the seed coat endothelium of Arabidopsis thaliana
Authors: Baxter IR, Young JC, Armstrong G, Foster N, Bogenschutz N, Cordova T, Peer WA, Hazen SP, Murphy AS, Harper JF.
Journal: Proc Natl Acad Sci U S A (2005): 2649

Expression and activity of multidrug resistance protein 1 in a murine thymoma cell line
Authors: Echevarria-Lima J, Kyle-Cezar F, DF PL, Capella L, Capella MA, Rumjanek VM.
Journal: Immunology (2005): 468

Homocysteinic acid causes oxidative stress in lymphocytes by potentiating toxic effect of NMDA
Authors: Boldyrev AA.
Journal: Bull Exp Biol Med (2005): 33