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刚果红 CAS 573-58-0

英文名称:Congo Red *UltraPure grade* *CAS 573-58-0*
产品参数
Ex (nm)-Em (nm)-
分子量696.66溶剂Water
存储条件在零下15度以下保存, 避免光照
产品概述

产品基本信息

产品名称:刚果红

CAS:573-58-0

储存条件:-15℃避光防潮

保质期:24个月

 

产品物理化学光谱特性

分子量:696.66

溶剂:水

激发波长(nm):497

发射波长(nm):N/A

 

产品介绍

刚果红(CR)是联苯二重氮-双-1-萘胺-4-磺酸的钠盐。 CR是水溶性的,产生红色胶体溶液。 在组织学中用于染色细胞质和红细胞。淀粉样蛋白沉积以及与其他原纤维沉积物的分化的早期诊断和分类取决于常规的CR组织化学。 该组织学测定法广泛用于体外淀粉样蛋白原纤维的表征。 此外,CR还用于淀粉样蛋白原纤维的荧光检测。 与强光下的CR相比,CR荧光易于执行且效果明显。 尽管未广泛使用,但是用于检测淀粉样蛋白的CR荧光法操作简便,特异性高,灵敏度高,可成功应用于冷冻切片。百萤生物是AAT Bioquest的中国代理商,为您提供优质的刚果红。 

 

参考文献

The effects of sodium sulfate, glycosaminoglycans, and Congo red on the structure, stability, and amyloid formation of an immunoglobulin light-chain protein
Authors: McLaughlin RW, De Stigter JK, Sikkink LA, Baden EM, Ramirez-Alvarado M.
Journal: Protein Sci (2006): 1710

Acetylcholinesterase-amyloid-beta-peptide interaction: effect of Congo Red and the role of the Wnt pathway
Authors: Inestrosa NC, Alvarez A, Dinamarca MC, Perez-Acle T, Colombres M.
Journal: Curr Alzheimer Res (2005): 301

Alzheimer's beta-amyloid: insights into fibril formation and structure from Congo red binding
Authors: Inouye H, Kirschner DA.
Journal: Subcell Biochem (2005): 203

Improved detection of amyloid in fat pad aspiration: an evaluation of Congo red stain by fluorescent microscopy
Authors: Giorgadze TA, Shiina N, Baloch ZW, Tomaszewski JE, Gupta PK.
Journal: Diagn Cytopathol (2004): 300

Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation
Authors: Kim YS, R and olph TW, Manning MC, Stevens FJ, Carpenter JF.
Journal: J Biol Chem (2003): 10842

Pinacyanol as effective probe of fibrillar beta-amyloid peptide: comparative study with Congo Red
Authors: Sabate R, Estelrich J.
Journal: Biopolymers (2003): 455

Congo-red negative colonic amyloid with scalloping of the valvulae conniventes
Authors: Michael H, Br and t LJ, Tanaka KE, Berkowitz D, Cardillo M, Weidenheim K.
Journal: Gastrointest Endosc (2001): 653

Evidence that supramolecular Congo red is the sole ligation form of this dye for L chain lambda derived amyloid proteins
Authors: Rybarska J, Piekarska B, Stopa B, Zemanek G, Konieczny L, Nowak M, Krol M, Roterman I, Szymczakiewicz-Multanowska A.
Journal: Folia Histochem Cytobiol (2001): 307

Is Congo red an amyloid-specific dye
Authors: Khurana R, Uversky VN, Nielsen L, Fink AL.
Journal: J Biol Chem (2001): 22715

Why Congo red binding is specific for amyloid proteins - model studies and a computer analysis approach
Authors: Roterman I, KrUl M, Nowak M, Konieczny L, Rybarska J, Stopa B, Piekarska B, Zemanek G.
Journal: Med Sci Monit (2001): 771