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吲哚菁绿ICG炔烃 CAS 1622335-40-3

英文名称:ICG alkyne
产品参数
Ex (nm)789Em (nm)813
分子量768.03溶剂DMSO
存储条件在零下15度以下保存, 避免光照
产品概述

产品基本信息

产品名称:吲哚菁绿ICG炔烃

CAS:1622335-40-3

储存条件:-15℃避光防潮

保质期:24个月

 

产品物理化学光谱特性

分子量:768.03

外观:固体

溶剂:DMSO

激发波长(nm):780

发射波长(nm):800

 

产品介绍

吲哚菁绿(ICG)是一种三碳菁型染料,具有NIR吸收特性(峰值吸收约780 nm),大发射波长约为800 nm。这种染料也称为Cardio Green和其他一些较不常见的商品名。 FDA批准了非侵入性近红外(NIR)荧光成像染料ICG进行眼科血管造影,以确定心输出量以及肝血流量和功能。由于红外频率穿透视网膜层,因此与荧光素血管造影相比,ICG血管造影可以成像更深的循环模式。 ICG与血浆蛋白紧密结合,并局限于血管系统。 ICG的半衰期为150到180秒,只能从肝脏转移至胆汁而从循环系统中移除。近的一项研究表明,ICG可在注射后20分钟内靶向动脉粥样硬化,并为体内检测动脉粥样硬化兔中富含脂质,发炎,冠状动脉粥样斑块提供了足够的信号增强。离体荧光反射成像显示,与注射盐水的带有粥样斑块的兔子相比,注射了ICG的带有粥样斑块的兔子的斑块靶标与背景比率高。它还可用于其他医学诊断和癌症患者中,用于实体瘤的检测,淋巴结的定位以及在重建手术期间的血管造影,视网膜和脉络膜血管的可视化以及光动力疗法。在癌症诊断和治疗中,ICG既可以用作显像染料又可以用作热疗剂。在可见光范围内几乎没有吸收,这是由于低自发荧光,组织吸收和在近红外波长(700-900 nm)下的散射引起的。这种ICG炔烃可用于通过众所周知的点击化学方法化学选择性标记叠氮基(叠氮化物)标记的生物分子(如蛋白质,脂质,核酸,糖)。百萤生物是AAT Bioquest的中国代理商,为您提供优质的吲哚菁绿ICG炔烃。 

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参考文献

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Single-Layer MoS2 Nanosheets with Amplified Photoacoustic Effect for Highly Sensitive Photoacoustic Imaging of Orthotopic Brain Tumors
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A simple and effective technique for identification of intersegmental planes by infrared thoracoscopy after transbronchial injection of indocyanine green
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Anatomic response of occult choroidal neovascularization to intravitreal ranibizumab: a study by indocyanine green angiography
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Applicability of radiocolloids, blue dyes and fluorescent indocyanine green to sentinel node biopsy in melanoma
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