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荧光底物Leu-AMC [L-亮氨酸-7-酰胺基-4-甲基香豆素] CAS 62480-44-8

英文名称:Leu-AMC [L-Leucine-7-amido-4-methylcoumarin] *CAS 62480-44-8*
产品参数
Ex (nm)341Em (nm)441
分子量324.80溶剂DMSO
存储条件在零下15度以下保存, 避免光照
产品概述

产品基本信息

产品名称:荧光底物Leu-AMC [L-亮氨酸-7-酰胺基-4-甲基香豆素]

CAS:62480-44-8

储存条件:-15℃避光防潮

保质期:24个月

 

产品物理化学光谱特性

分子量:324.80

溶剂:DMSO

激发波长(nm):351

发射波长(nm):430

 

产品介绍

荧光底物Leu-AMC [L-亮氨酸-7-酰胺基-4-甲基香豆素]是美国AAT Bioquest生产的荧光染料,Leu-AMC是亮氨酸氨肽酶的荧光底物。 在蛋白酶水解后,Leu-AMC释放出强烈荧光的AMC荧光团,其可以用Ex / Em = 350 / 430nm容易地检测。百萤生物是AAT Bioquest的中国代理商,为您提供最优质的荧光底物Leu-AMC [L-亮氨酸-7-酰胺基-4-甲基香豆素]。 

点击查看光谱

 

参考文献

Molecular and biochemical characterization of methionine aminopeptidase of Babesia bovis as a potent drug target
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Journal: Vet Parasitol (2016): 14

Secretory Expression, Purification, Characterization, and Application of an Aspergillus oryzae Prolyl Aminopeptidase in Bacillus subtilis
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Journal: Appl Biochem Biotechnol. (2016)

Essential Role for an M17 Leucine Aminopeptidase in Encystation of Acanthamoeba castellanii
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Journal: PLoS One (2015): e0129884

Inhibition of leucine aminopeptidase 3 suppresses invasion of ovarian cancer cells through down-regulation of fascin and MMP-2/9
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Journal: Eur J Pharmacol (2015): 116

Molecular Characterization of Babesia bovis M17 Leucine Aminopeptidase and Inhibition of Babesia Growth by Bestatin
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Journal: J Parasitol (2015): 536

Modelling of human leucyl aminopeptidases for in silico off target binding analysis of potential Plasmodium falciparum leucine aminopeptidase (PfA-M17) specific inhibitors
Authors: Sahi S, Raj U, Chaudhary M, Nain V.
Journal: Recent Pat Endocr Metab Immune Drug Discov (2014): 191

Design, synthesis and preliminary activity evaluation of novel 3-amino-2-hydroxyl-3-phenylpropanoic acid derivatives as aminopeptidase N/CD13 inhibitors
Authors: Zhang X, Zhang L, Zhang J, Feng J, Yuan Y, Fang H, Xu W.
Journal: J Enzyme Inhib Med Chem (2013): 545

Enzymatic and molecular characterisation of leucine aminopeptidase of Burkholderia pseudomallei
Authors: Liew SM, Tay ST, Puthucheary SD.
Journal: BMC Microbiol (2013): 110

Exploration of structural and physicochemical requirements and search of virtual hits for aminopeptidase N inhibitors
Authors: Halder AK, Saha A, Jha T.
Journal: Mol Divers (2013): 123

Novel leucine ureido derivatives as inhibitors of aminopeptidase N (APN)
Authors: Ma C, Jin K, Cao J, Zhang L, Li X, Xu W.
Journal: Bioorg Med Chem (2013): 1621