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N6-甲基腺苷-生物素缀合物

英文名称:N6-Methyladenosine-Biotin conjugate
产品参数
Ex (nm)-Em (nm)-
分子量753.87溶剂DMSO
存储条件在零下15度以下保存, 避免光照
产品概述

产品基本信息

产品名称:N6-甲基腺苷-生物素缀合物

储存条件:-15℃避光防潮

保质期:24个月

 

产品物理化学光谱特性

分子量:753.87

外观:固体

溶剂:DMSO

 

产品介绍

N-6甲基腺苷(m6A)是目前已知的100余种RNA甲基化修饰中普遍存在的一种,存在于某些病毒和大多数真核生物中,包括哺乳动物,昆虫,植物和酵母。 在tRNA,rRNA和小核RNA(snRNA)以及一些长的非编码RNA(例如Xist)中也发现了它。 腺苷的甲基化由包含METTL3作为SAM结合亚基的大型N6-甲基腺苷甲基转移酶复合物控制。 m6A的生物学功能是通过一组RNA结合蛋白介导的,这些蛋白特异性识别RNA上的甲基化腺苷。 该生物素化的N6-甲基腺苷衍生物可以用于检测与N6-甲基腺苷有关的RNA修饰。百萤生物是AAT Bioquest的中国代理商,为您提供优质的N6-甲基腺苷-生物素缀合物。 

 
参考文献
 
Changes of RNA N(6)-methyladenosine in the hormesis effect induced by arsenite on human keratinocyte cells
Authors: Chen, H., Zhao, T., Sun, D., Wu, M., Zhang, Z.
Journal: Toxicol In Vitro (2019): 84-92
 
N6-methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO-PGC-1alpha signalling axis
Authors: Zhuang, C., Zhuang, C., Luo, X., Huang, X., Yao, L., Li, J., Li, Y., Xiong, T., Ye, J., Zhang, F., Gui, Y.
Journal: J Cell Mol Med (2019): 2163-2173
 
A dynamic reversible RNA N(6) -methyladenosine modification: current status and perspectives
Authors: Bi, Z., Liu, Y., Zhao, Y., Yao, Y., Wu, R., Liu, Q., Wang, Y., Wang, X.
Journal: J Cell Physiol (2019): 7948-7956
 
Transcriptome-wide analysis of N6-methyladenosine uncovers its regulatory role in gene expression in the lepidopteran Bombyx mori
Authors: Li, B., Wang, X., Li, Z., Lu, C., Zhang, Q., Chang, L., Li, W., Cheng, T., Xia, Q., Zhao, P.
Journal: Insect Mol Biol (2019): se name="17100.enl" path="C:\Users\aatbi\Drop
 
RNA N6-methyladenosine modification participates in miR-660/E2F3 axis-mediated inhibition of cell proliferation in gastric cancer
Authors: He, X., Shu, Y.
Journal: Pathol Res Pract (2019): se name="17100.enl" path="C:\Users\aatbi\Drop
 
Importance of m N(6)-methyladenosine (m(6)A) RNA modification in cancer
Authors: Tuncel, G., Kalkan, R.
Journal: Med Oncol (2019): 36
 
The role of N(6)-methyladenosine RNA methylation in the heat stress response of sheep (Ovis aries)
Authors: Lu, Z., Ma, Y., Li, Q., Liu, E., Jin, M., Zhang, L., Wei, C.
Journal: Cell Stress Chaperones (2019): 333-342
 
Epitranscriptomics: Correlation of N6-methyladenosine RNA methylation and pathway dysregulation in the hippocampus of HIV transgenic rats
Authors: Fu, Y., Zorman, B., Sumazin, P., Sanna, P. P., Repunte-Canonigo, V.
Journal: PLoS One (2019): e0203566
 
Identifying N(6)-methyladenosine sites using extreme gradient boosting system optimized by particle swarm optimizer
Authors: Zhao, X., Zhang, Y., Ning, Q., Zhang, H., Ji, J., Yin, M.
Journal: J Theor Biol (2019): 39-47
 
N1-Methyladenosine detection with CRISPR-Cas13a/C2c2
Authors: Chen, Y., Yang, S., Peng, S., Li, W., Wu, F., Yao, Q., Wang, F., Weng, X., Zhou, X.
Journal: Chem Sci (2019): 2975-2979