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细胞抑制剂(-)-Blebbistatin CAS 856925-71-8

英文名称:(-)-Blebbistatin *CAS#: 856925-71-8*
产品参数
Ex (nm)-Em (nm)-
分子量292.33溶剂-
存储条件-
产品概述

产品基本信息

产品名称:细胞抑制剂(-)-Blebbistatin

CAS:856925-71-8

储存条件:-15℃避光防潮

保质期:12个月

 

产品物理化学光谱特性

分子量:292.33

溶剂:DMSO

 

产品介绍

(-)-Blebbistatin是非肌肉肌球蛋白II ATPase的细胞可渗透抑制剂,IC50为2 µM。 它不抑制肌球蛋白轻链激酶,在不破坏有丝分裂或可收缩环组装的情况下,抑制卵裂沟的收缩。百萤生物是AAT Bioquest的中国代理商,为您提供优质的细胞抑制剂(-)-Blebbistatin。

 

参考文献

Homology model of nonmuscle myosin heavy chain IIA and binding mode analysis with its inhibitor blebbistatin
Authors: Lv Y, Lu S, Lu T, Kou J, Yu B.
Journal: J Mol Model (2013): 1801

The mechanical uncoupler blebbistatin is associated with significant electrophysiological effects in the isolated rabbit heart
Authors: Brack KE, Narang R, Winter J, Ng GA.
Journal: Exp Physiol (2013): 1009

Blebbistatin, a myosin inhibitor, is phototoxic to human cancer cells under exposure to blue light
Authors: Mikulich A, Kavaliauskiene S, Juzenas P.
Journal: Biochim Biophys Acta (2012): 870

Enrichment of cell populations in metaphase, anaphase, and telophase by synchronization using nocodazole and blebbistatin: a novel method suitable for examining dynamic changes in proteins during mitotic progression
Authors: Matsui Y, Nakayama Y, Okamoto M, Fukumoto Y, Yamaguchi N.
Journal: Eur J Cell Biol (2012): 413

Modifications of mechanoelectric feedback induced by 2,3-butanedione monoxime and Blebbistatin in Langendorff-perfused rabbit hearts
Authors: Brines L, Such-Miquel L, Gallego D, Trapero I, Del Canto I, Zarzoso M, Soler C, Pelechano F, Canoves J, Alberola A, Such L, Chorro FJ.
Journal: Acta Physiol (Oxf) (2012): 29

Properties of blebbistatin for cardiac optical mapping and other imaging applications
Authors: Swift LM, Asfour H, Posnack NG, Arutunyan A, Kay MW, Sarvazyan N.
Journal: Pflugers Arch (2012): 503

The role of dynamic instability and wavelength in arrhythmia maintenance as revealed by panoramic imaging with blebbistatin vs. 2,3-butanedione monoxime
Authors: Lou Q, Li W, Efimov IR.
Journal: Am J Physiol Heart Circ Physiol (2012): H262

Application of the copper catalysed N-arylation of amidines in the synthesis of analogues of the chemical tool, blebbistatin
Authors: Lawson CP, Slawin AM, Westwood NJ.
Journal: Chem Commun (Camb) (2011): 1057

In vitro and in vivo relaxation of urinary bladder smooth muscle by the selective myosin II inhibitor, blebbistatin
Authors: Zhang X, Kuppam DS, Melman A, DiSanto ME.
Journal: BJU Int (2011): 310

Inhibition of suicidal erythrocyte death by blebbistatin
Authors: Lang E, Qadri SM, Zelenak C, Gu S, Rotte A, Draeger A, Lang F.
Journal: Am J Physiol Cell Physiol (2011): C490