四甲基罗丹明乙酯 TMRE CAS 115532-52-0
英文名称：TMRE [Tetramethylrhodamine ethyl ester] *CAS#: 115532-52-0*
产品参数
| Ex (nm) | 552 | Em (nm) | 574 |
| 分子量 | 514.95 | 溶剂 | DMSO |
| 存储条件 | 在零下15度以下保存, 避免光照 |
产品概述
产品货期
咨询
产品优势
1.高特异性：依赖于线粒体膜电位（ΔΨm）选择性积聚在活性线粒体中
2..稳定性好：抗光漂白能力强，适合长时间活细胞成像
3.高信噪比：和其他染料相比，信噪比更高，成像更清晰
适用范围
用于活细胞线粒体标记
产品简介
带正电荷的罗丹明染料（如罗丹明酯类和玫瑰胺类）能特异性积聚于线粒体，因此被广泛用于活细胞线粒体标记。其中，TMRM（四甲基罗丹明甲酯）和TMRE（四甲基罗丹明乙酯）与JC-1类似，除用于线粒体特异性染色外，还可检测线粒体膜电位（ΔΨm）。这两种染料可使线粒体呈现明亮的橙色荧光（激发/发射波长：548/573 nm），其光谱特性与TRITC高度相似，便于使用常规荧光显微镜的TRITC滤光片组进行观察。值得注意的是，由于乙酯基团比甲酯基团多一个亚甲基，TMRE的疏水性略高于TMRM，这一特性使TMRE在神经元等难转染细胞中具有更好的穿透效率，但同时也可能增加非特异性结合的风险。
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